Meso-2,3-dimercaptosuccinic acid (DMSA) is a sulfhydryl-containing, water-soluble, non-toxic, orally administered, metal chelator which has been in use as an antidote to heavy metal toxicity since the 1950s. It is also known as succimer and sold as a prescription under the trade name Chemet. DMPS chelation is most commonly used to remove lead in both adults and children, although it may also be used for mercury poisoning and for dangerous levels of other heavy metals. Clinical use and research substantiates this compound’s efficacy and safety.
Altern Med Rev 2000; 5 (3): 264-7